Sugi Predict

Sugi Predict / Compounds / SCHEMBL19923722

SCHEMBL19923722

SCHEMBL19923722

CC(C)N1C(=O)N([Si](C)(C)C)C(c2ccccc2)(C(C)C)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ USP2 O75604 2/20 0.35
▸ ALDH1A1 P00352 4/20 0.34
▸ MARK3 P27448 1/20 0.34
▸ ADAMTS5 Q9UNA0 1/20 0.34
▸ TDP1 Q9NUW8 2/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ NPSR1 Q6W5P4 1/20 0.33
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ ATM Q13315 1/20 0.32
▸ REN P00797 1/20 0.32
▸ APP P05067 1/20 0.32
▸ BACE1 P56817 1/20 0.32
▸ BACE2 Q9Y5Z0 1/20 0.32
▸ MMP1 P03956 1/20 0.32
▸ MMP2 P08253 1/20 0.32
▸ MMP9 P14780 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923770 0.87 SMN1; SMN2 (0.35) SMN1; SMN2USP2ALDH1A1MARK3ADAMTS5
SCHEMBL19923479 0.86 USP2 (0.36) SMN1; SMN2USP2ALDH1A1MARK3ADAMTS5
SCHEMBL19923401 0.85 SMN1; SMN2 (0.33) SMN1; SMN2USP2ALDH1A1MARK3ADAMTS5
SCHEMBL19923446 0.68 SMN1; SMN2 (0.41) SMN1; SMN2USP2ALDH1A1MARK3ADAMTS5
SCHEMBL19923632 0.68 USP2 (0.35) SMN1; SMN2USP2ALDH1A1MARK3ADAMTS5
SCHEMBL19923569 0.67 SMN1; SMN2 (0.40) SMN1; SMN2USP2ALDH1A1MARK3MEN1
SCHEMBL19923678 0.66 ELANE (0.35) SMN1; SMN2USP2ALDH1A1MARK3ADAMTS5
SCHEMBL19923579 0.65 SMN1; SMN2 (0.38) SMN1; SMN2USP2ALDH1A1TDP1L3MBTL1
SCHEMBL1919973 0.64 KMT2A (0.60) SMN1; SMN2ALDH1A1GAAMAPTMEN1
SCHEMBL19923688 0.64 ALDH1A1 (0.37) SMN1; SMN2ALDH1A1RENAPPBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 — — US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 — — US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 — — US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN SMN1; SMN2 1697/4885USP2 962/4885ALDH1A1 2648/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM SMN1; SMN2 1924/4885USP2 975/4885ALDH1A1 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.