SCHEMBL26548503

SCHEMBL26548503

N[C@@H](CCCCNC(=S)CCCc1ccc([131I])cc1)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALB P02768 3/20 0.41
SIRT2 Q8IXJ6 4/20 0.39
SIRT1 Q96EB6 3/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
GRIK1 P39086 1/20 0.38
SLC5A1 P13866 1/20 0.38
LTA4H P09960 1/20 0.37
PLAAT3 P53816 2/20 0.37
PLAAT5 Q96KN8 2/20 0.37
PLAAT2 Q9NWW9 2/20 0.37
PLAAT4 Q9UL19 2/20 0.37
SIRT3 Q9NTG7 2/20 0.37
LMNA P02545 1/20 0.36
PKM P14618 1/20 0.36
SIRT5 Q9NXA8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19929583 0.94 CA12 (0.39) ALBSIRT2SIRT1CA12CA1
SCHEMBL19924298 0.88 ALB (0.54) ALBSIRT2SIRT1CA12CA1
SCHEMBL22021344 0.88 PLAAT3 (0.48) ALBSIRT2SIRT1CA12CA1
SCHEMBL19929586 0.88 ALB (0.41) ALBSIRT2SIRT1CA12CA1
SCHEMBL19924296 0.88 ALB (0.54) ALBSIRT2SIRT1CA12CA1
SCHEMBL26548495 0.88 ALB (0.41) ALBSIRT2SIRT1CA12CA1
SCHEMBL19929584 0.88 ALB (0.41) ALBSIRT2SIRT1CA12CA1
SCHEMBL19929580 0.88 ALB (0.53) ALBSLC5A1LMNAPKM
SCHEMBL19929571 0.86 ALB (0.43) ALBSIRT2SIRT1SIRT3LMNA
SCHEMBL19929585 0.84 HPGD (0.49) ALBSLC5A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2023-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IL1RN, IL2RA, IL1A ALB 31/4885SIRT2 2885/4885SIRT1 2138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.