Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5521124 | 0.76 | GPR119 (0.33) | GPR119 | |
| SCHEMBL27861037 | 0.74 | GPR119 (0.32) | GPR119DPP4 | |
| SCHEMBL6658943 | 0.74 | GPR119 (0.32) | GPR119 | |
| SCHEMBL3716933 | 0.74 | — | — | |
| SCHEMBL15955662 | 0.72 | DPP7 (0.38) | DPP7 | |
| SCHEMBL16335754 | 0.72 | DPP7 (0.38) | DPP7 | |
| Hydrochloric Acid SCHEMBL16992665 | 0.72 | DPP7 (0.33) | DPP7 | |
| SCHEMBL7459218 | 0.71 | NOTUM (0.38) | — | |
| SCHEMBL24734683 | 0.70 | DPP4 (0.37) | GPR119DPP4 | |
| SCHEMBL8891712 | 0.69 | KCNH2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507281-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018041964-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2018-03-08 | — | — | WO | disclosed |