Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900895 | 0.86 | — | — | |
| SCHEMBL422753 | 0.79 | HRH3 (0.46) | GPR119HRH3LMNACYP2C9 | |
| SCHEMBL6745627 | 0.77 | MEN1 (0.39) | — | |
| SCHEMBL27496417 | 0.77 | GNAI3 (0.33) | DPP4 | |
| SCHEMBL22565324 | 0.77 | GPR119 (0.37) | GPR119HRH3LMNACYP2C9 | |
| SCHEMBL1492459 | 0.77 | MEN1 (0.39) | — | |
| SCHEMBL23103238 | 0.75 | GPR119 (0.36) | GPR119HRH3LMNACYP2C9 | |
| SCHEMBL18950401 | 0.75 | GPR119 (0.36) | GPR119HRH3LMNACYP2C9 | |
| SCHEMBL23108661 | 0.75 | GPR119 (0.36) | GPR119HRH3LMNACYP2C9 | |
| SCHEMBL6841703 | 0.75 | GPR119 (0.36) | GPR119HRH3LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022256459-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2022-12-08 | — | — | WO | disclosed |