Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955662 | 1.00 | DPP7 (0.38) | DPP7FDPSLMNAMAPTHTT | |
| SCHEMBL3716933 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL16992665 | 0.95 | DPP7 (0.33) | DPP7FDPSLMNAMAPTHTT | |
| SCHEMBL8590 | 0.75 | — | — | |
| SCHEMBL1821639 | 0.75 | MEN1 (0.33) | ANPEPERAP2 | |
| SCHEMBL1934289 | 0.74 | DPP7 (0.33) | DPP7FDPS | |
| Hydrochloric Acid SCHEMBL4054696 | 0.73 | CYP2D6 (0.32) | — | |
| Hydrochloric Acid SCHEMBL20899797 | 0.73 | MAPT (0.38) | LMNAMAPTANPEP | |
| SCHEMBL4430883 | 0.72 | FDPS (0.39) | DPP7FDPSLMNAMAPTHTT | |
| SCHEMBL19924840 | 0.72 | GPR119 (0.32) | DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3126345-A1 | INHIBITORS OF HISTONE DEMETHYLASES | Gilead Sciences, Inc. (US) | 2017-02-08 | — | — | EP | disclosed |
| EP-3013828-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2016-05-04 | — | — | EP | disclosed |
| WO-2015153498-A1 | INHIBITORS OF HISTONE DEMETHYLASES | EPITHERAPEUTICS, APS (DK) | 2015-10-08 | — | — | WO | disclosed |
| WO-2014206150-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2014-12-31 | — | — | WO | disclosed |