Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9983691 | 0.70 | CA12 (0.35) | CA12CA1CA2CA9CA4 | |
| SCHEMBL3714644 | 0.65 | CA12 (0.35) | CA12CA1CA2CA9CA4 | |
| SCHEMBL1947435 | 0.64 | CA12 (0.34) | CA12CA1CA2CA9CA4 | |
| SCHEMBL29374033 | 0.64 | CA12 (0.46) | CA12CA1CA2CA9CA4 | |
| SCHEMBL2563736 | 0.64 | CA12 (0.46) | CA12CA1CA2CA9CA4 | |
| SCHEMBL9551845 | 0.62 | GPR3 (0.39) | CA12CA1CA2CA9CA4 | |
| SCHEMBL6228752 | 0.62 | GPR3 (0.39) | CA12CA1CA2CA9CA4 | |
| SCHEMBL1450925 | 0.60 | GPR3 (0.37) | CA12CA1CA2CA9CA4 | |
| SCHEMBL5485319 | 0.60 | GPR3 (0.37) | CA12CA1CA2CA9CA4 | |
| SCHEMBL8336188 | 0.60 | CA12 (0.64) | CA12CA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2344494-B1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARM LLC (US) | 2016-04-20 | — | — | EP | claimed |
| US-8299056-B2 | Aminotriazolopyridines, compositions thereof, and methods of treatment therewith | SIGNAL PHARMACEUTICALS, LLC (US) | 2012-10-30 | — | — | US | claimed |
| EP-2344494-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | Signal Pharmaceuticals, LLC (US) | 2011-07-20 | — | — | EP | claimed |
| US-20100093698-A1 | AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC | 2010-04-15 | — | — | US | claimed |
| WO-2010027500-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-03-11 | — | — | WO | claimed |
| US-10131646-B2 | Aromatic sulfonium salt compound, photoacid generator, resist composition, cationic polymerization initiator, and cationically polymerizable composition | ADEKA CORPORATION (JP) | 2018-11-20 | — | — | US | disclosed |
| US-20180079738-A1 | AROMATIC SULFONIUM SALT COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR, AND CATIONICALLY POLYMERIZABLE COMPOSITION | ADEKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| EP-3272744-A1 | AROMATIC SULFONIUM SALT COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR, AND CATIONICALLY POLYMERIZABLE COMPOSITION | Adeka Corporation (JP) | 2018-01-24 | — | — | EP | disclosed |
| EP-2344494-B1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARM LLC (US) | 2016-04-20 | — | — | EP | disclosed |
| US-9073854-B2 | Aromatic sulfonium salt compound | ADEKA CORPORATION (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-2502915-B1 | AROMATIC SULFONIUM SALT COMPOUND | ADEKA CORP (JP) | 2015-03-18 | — | — | EP | disclosed |
| US-20130005707-A1 | AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | BAHMANYAR SOGOLE (US) | 2013-01-03 | — | — | US | disclosed |
| WO-2010027500-A1 | AMINOTRIAZOLOPYRIDINES AND THEIR USE AS KINASE INHIBITORS | SIGNAL PHARMACEUTICALS, LLC (US) | 2010-03-11 | — | — | WO | disclosed |
| EP-1109071-A1 | 2-(1,2-benzisothiazol-3(2h)-ylidene 1,1-dioxide)acetamides negative charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |
| US-6184387-B1 | 2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)acetamides negative charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-02-06 | — | — | US | disclosed |
| US-6165668-A | N-[2-(1,2-benzisothiazol-3(2H)-ylidene 1,1-dioxide)-2-cyanoacetyl]benzenesulfonamide charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| US-6120964-A | TONERS WITH BINDERS | EASTMAN KODAK COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| US-5849450-A | (1,2-benzisothiazol-3-(2H)-ylidene 1,1-dioxide) acetate-terminated polymer charge-control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5744277-A | Electrostatographic toners and developers containing (1,2-benzisothiazol-3-(2H)-ylidene 1,1-dioxide) acetate-terminated polymer charge-control agents | EASTMAN KODAK COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| US-5723248-A | Electrostatographic toners and developers containing bis 1,2-benzisthiazol-3(2h) -ylidene 1,1-dioxide) acetates!charge-control agents | EASTMAN KODAK COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005707-A1 | AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | MAP3K2, MAP3K1, MAP3K3 | CA12 4880/4885CA1 4826/4885CA2 4075/4885 |
| US-10131646-B2 | Aromatic sulfonium salt compound, photoacid generator, resist composition, cationic polymerization initiator, and cationically polymerizable composition | ASIC1, NOX5, SLC6A19 | CA12 231/4885CA1 166/4885CA2 21/4885 |
| US-20100093698-A1 | AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | MAP3K2, MAP3K1, MAP3K3 | CA12 4880/4885CA1 4826/4885CA2 4075/4885 |
| US-20180079738-A1 | AROMATIC SULFONIUM SALT COMPOUND, PHOTOACID GENERATOR, RESIST COMPOSITION, CATIONIC POLYMERIZATION INITIATOR, AND CATIONICALLY POLYMERIZABLE COMPOSITION | ASIC1, NOX5, SLC6A19 | CA12 231/4885CA1 166/4885CA2 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.