SCHEMBL19927447

SCHEMBL19927447

C[SiH](C)O[SiH](Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.39
TSHR P16473 4/20 0.37
CALM1 P0DP23 1/20 0.36
ALDH1A1 P00352 4/20 0.34
IDO1 P14902 2/20 0.34
LTA4H P09960 1/20 0.34
KDM4E B2RXH2 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MAPT P10636 2/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
AGXT P21549 1/20 0.33
TRPA1 O75762 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TAAR1 Q96RJ0 2/20 0.32
MAOA P21397 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28446741 0.85 TSHR (0.43) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL21112710 0.82 TP53 (0.39) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL19926912 0.80 TP53 (0.42) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL19926925 0.77 TAAR1 (0.38) TP53TSHRALDH1A1MAPTTRPA1
SCHEMBL3482739 0.76 TP53 (0.42) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL28729720 0.74 TSHR (0.33) TP53TSHRCALM1ALDH1A1TAAR1
SCHEMBL3482077 0.73 TP53 (0.44) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL6960735 0.72 TP53 (0.48) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL476128 0.72 TP53 (0.48) TP53TSHRCALM1ALDH1A1IDO1
SCHEMBL4355746 0.71 TSHR (0.46) TP53TSHRCALM1ALDH1A1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507104-B1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU BRIDGESTONE CORP (JP) 2024-03-27 EP disclosed
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
US-10975178-B2 Production of cis-1,4-polydienes with multiple silane functional groups prepared by in-situ hydrosilylation of polymer cement BRIDGESTONE CORPORATION (JP) 2021-04-13 US disclosed
US-20190211120-A1 Production Of Cis-1,4-Polydienes With Multiple Silane Functional Groups Prepared By In-Situ Hydrosilylation Of Polymer Cement BRIDGESTONE CORPORATION (JP) 2019-07-11 US disclosed
EP-3507104-A1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BYIN-SITU Bridgestone Corporation (JP) 2019-07-10 EP disclosed
WO-2018045291-A1 PRODUCTION OF CIS-1,4-POLYDIENES WITH MULTIPLE SILANE FUNCTIONAL GROUPS PREPARED BY IN-SITU HYDROSILYLATION OF POLYMER CEMENT BRIDGESTONE CORPORATION (JP) 2018-03-08 WO disclosed