Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25275768 | 0.83 | GPR119 (0.40) | GPR119USP30PTPN2PTPN1PTPN6 | |
| SCHEMBL19895869 | 0.78 | GPR119 (0.36) | GPR119 | |
| SCHEMBL19895842 | 0.72 | ALDH1A1 (0.35) | GPR119 | |
| SCHEMBL30892162 | 0.71 | GAA (0.42) | GPR119 | |
| SCHEMBL25519242 | 0.71 | GPR119 (0.38) | GPR119USP30PTPN2PTPN1PTPN6 | |
| SCHEMBL34473874 | 0.71 | SCD5 (0.46) | GPR119 | |
| SCHEMBL13160787 | 0.71 | SCD5 (0.46) | GPR119 | |
| SCHEMBL34473876 | 0.71 | SCD5 (0.46) | GPR119 | |
| SCHEMBL31569206 | 0.70 | GPR119 (0.46) | GPR119 | |
| SCHEMBL22102480 | 0.69 | GPR119 (0.40) | GPR119USP30PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3503889-A1 | INHIBITORS OF DUAL LEUCINE ZIPER (DLK) KINASE FOR THE TREATMENT OF DISEASE | Board Of Regents, The University Of Texas System (US) | 2019-07-03 | — | — | EP | disclosed |
| WO-2018044808-A1 | INHIBITORS OF DUAL LEUCINE ZIPER (DLK) KINASE FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM (US) | 2018-03-08 | — | — | WO | disclosed |