Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996984 | 0.88 | L3MBTL1 (0.65) | L3MBTL1HTR6PTGDR2EPHX1FEN1 | |
| SCHEMBL28935614 | 0.88 | L3MBTL1 (0.46) | L3MBTL1HTR6PTGDR2EPHX1FEN1 | |
| SCHEMBL28935624 | 0.88 | PTGDR2 (0.48) | L3MBTL1HTR6PTGDR2EPHX1AKR1C3 | |
| SCHEMBL28935653 | 0.84 | L3MBTL1 (0.43) | L3MBTL1HTR6PTGDR2EPHX1FEN1 | |
| SCHEMBL1995369 | 0.81 | L3MBTL1 (0.49) | L3MBTL1HTR6PTGDR2EPHX1AKR1C3 | |
| SCHEMBL28935550 | 0.80 | L3MBTL1 (0.41) | L3MBTL1HTR6PTGDR2EPHX1FEN1 | |
| SCHEMBL2018732 | 0.78 | L3MBTL1 (0.78) | L3MBTL1HTR6EPHX1AKR1C3PDE10A | |
| SCHEMBL1992149 | 0.78 | L3MBTL1 (0.36) | L3MBTL1HTR6EPHX1FEN1BCHE | |
| SCHEMBL29651147 | 0.78 | L3MBTL1 (0.78) | L3MBTL1HTR6EPHX1AKR1C3PDE10A | |
| SCHEMBL28935605 | 0.77 | L3MBTL1 (0.43) | L3MBTL1HTR6PTGDR2EPHX1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | L3MBTL1 3898/4885HTR6 368/4885PTGDR2 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.