Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25564484 | 0.83 | MEN1 (0.40) | EPHX1POLBMEN1KMT2A | |
| SCHEMBL8962258 | 0.78 | EPHX1 (0.37) | EPHX1POLBMEN1KMT2A | |
| SCHEMBL11947831 | 0.78 | EPHX1 (0.37) | EPHX1POLBMEN1KMT2A | |
| SCHEMBL27424921 | 0.76 | — | — | |
| SCHEMBL20953659 | 0.71 | MEN1 (0.40) | EPHX1POLBMEN1KMT2A | |
| SCHEMBL153717 | 0.71 | L3MBTL1 (0.42) | EPHX1POLBMEN1KMT2A | |
| SCHEMBL20374990 | 0.70 | TSHR (0.38) | EPHX1POLBMEN1KMT2A | |
| SCHEMBL6276759 | 0.70 | EPHX1 (0.36) | EPHX1POLBMEN1KMT2A | |
| SCHEMBL24978003 | 0.70 | POLB (0.30) | POLB | |
| SCHEMBL17582670 | 0.70 | ALDH1A1 (0.33) | EPHX1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-9908853-B2 | Inhibitors of peptidyl arginine deiminase (PAD) enzymes and uses thereof | THE HOSPITAL FOR SICK CHILDREN (CA) | 2018-03-06 | — | — | US | disclosed |