SCHEMBL25564484

SCHEMBL25564484

CC(C)(C)NC(=O)C(C)(C)C(C)(C)C(=O)NC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
EPHX1 P07099 2/20 0.40
POLB P06746 3/20 0.39
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
EPHX2 P34913 1/20 0.32
EGFR P00533 1/20 0.31
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 3/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
CYP2C9 P11712 1/20 0.30
APEX1 P27695 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8962258 0.88 EPHX1 (0.37) MEN1KMT2AEPHX1POLBRAB9A
SCHEMBL19928199 0.83 EPHX1 (0.34) MEN1KMT2AEPHX1POLB
SCHEMBL153717 0.80 L3MBTL1 (0.42) MEN1KMT2AEPHX1POLBRAB9A
SCHEMBL20953659 0.80 MEN1 (0.40) MEN1KMT2AEPHX1POLBRAB9A
SCHEMBL6276759 0.79 EPHX1 (0.36) MEN1KMT2AEPHX1POLB
SCHEMBL18016462 0.78 ALDH1A1 (0.42) MEN1KMT2AEPHX1POLBRAB9A
SCHEMBL19608829 0.77 EPHX1 (0.34) MEN1KMT2AEPHX1POLBLMNA
SCHEMBL11977553 0.77 RIPK1 (0.42) MEN1KMT2AEPHX1POLBRAB9A
SCHEMBL20852999 0.75 EPHX1 (0.37) MEN1KMT2AEPHX1POLBRAB9A
SCHEMBL2757992 0.75 CA2 (0.48) MEN1KMT2AEPHX1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165882-A1 COMPOUNDS AND METHODS FOR REDUCTION OF CANCER CELL BURDEN AND PROTECTION OF NORMAL HEMATOPOIESIS GLYCOMIMETICS, INC. (US) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165882-A1 COMPOUNDS AND METHODS FOR REDUCTION OF CANCER CELL BURDEN AND PROTECTION OF NORMAL HEMATOPOIESIS FLT3, SELE, SELL MEN1 1391/4885KMT2A 1485/4885EPHX1 283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.