Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.44 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1993899 | 0.88 | L3MBTL1 (0.48) | KDM4EPKMMERTKCHRM2CHRM4 | |
| SCHEMBL1991129 | 0.85 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3GPR119 | |
| SCHEMBL1991126 | 0.85 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3GPR119 | |
| SCHEMBL1990506 | 0.85 | CHRM2 (0.47) | KDM4EPKMCHRM2CHRM4CHRM1 | |
| SCHEMBL31429443 | 0.83 | KDM4E (0.51) | KDM4EPKMMERTKCHRM2CHRM4 | |
| SCHEMBL15897969 | 0.83 | KDM4E (0.51) | KDM4EPKMMERTKCHRM2CHRM4 | |
| SCHEMBL1995835 | 0.82 | KDM4E (0.46) | KDM4EPKMMERTKCHRM2CHRM4 | |
| SCHEMBL1996234 | 0.81 | CNR1 (0.46) | KDM4EPADI4LMNASMN1; SMN2SSTR4 | |
| SCHEMBL31429521 | 0.81 | KDM4E (0.49) | KDM4EPKMMERTKCHRM2CHRM4 | |
| SCHEMBL23913676 | 0.80 | MAPT (0.53) | KDM4EPKMMERTKPIK3CDPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | KDM4E 3351/4885PKM 833/4885MERTK 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.