Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | MERTK | Q12866 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.42 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1994908 | 0.91 | L3MBTL1 (0.50) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1992840 | 0.88 | KDM4E (0.46) | MERTKKDM4EPKMSMN1; SMN2CHRM2 | |
| SCHEMBL1991437 | 0.86 | L3MBTL1 (0.44) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1991434 | 0.86 | L3MBTL1 (0.44) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL1998303 | 0.85 | RECQL (0.53) | RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL2002226 | 0.85 | L3MBTL1 (0.50) | L3MBTL1RECQLKDM4EALDH1A1PKM | |
| SCHEMBL1997456 | 0.84 | RECQL (0.55) | RECQLALDH1A1SMN1; SMN2 | |
| SCHEMBL1994772 | 0.83 | KDM4E (0.44) | L3MBTL1MERTKKDM4EPKMCHRM2 | |
| SCHEMBL1996881 | 0.83 | L3MBTL1 (0.48) | L3MBTL1RECQLKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1991871 | 0.83 | L3MBTL1 (0.48) | L3MBTL1RECQLALDH1A1SMN1; SMN2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | L3MBTL1 3898/4885RECQL 3604/4885MERTK 1792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.