Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313943 | 1.00 | FABP3 (0.41) | FABP3SMPD1PLA2G4ASMN1; SMN2PLA2G2A | |
| SCHEMBL19928629 | 0.87 | SMPD1 (0.52) | SMPD1SMN1; SMN2PLA2G2AMEN1S1PR1 | |
| SCHEMBL18826517 | 0.86 | PLA2G4A (0.44) | PLA2G4APLA2G2ATP53CYP1A2CYP2D6 | |
| SCHEMBL14192763 | 0.84 | PLA2G4A (0.58) | FABP3SMPD1PLA2G4APLA2G2APLA2G1B | |
| SCHEMBL16081282 | 0.83 | PLA2G4A (0.60) | FABP3SMPD1PLA2G4AMEN1S1PR1 | |
| SCHEMBL19928626 | 0.79 | S1PR1 (0.51) | FABP3SMPD1SMN1; SMN2MEN1S1PR1 | |
| SCHEMBL19010231 | 0.77 | FABP3 (0.44) | FABP3SMN1; SMN2PLA2G2APLA2G1BPLA2G10 | |
| SCHEMBL5959569 | 0.76 | PLA2G4A (0.54) | FABP3PLA2G4APLA2G2APLA2G1BMAPT | |
| SCHEMBL16181236 | 0.75 | PLA2G4A (0.44) | FABP3SMPD1PLA2G4ASMN1; SMN2PLA2G2A | |
| SCHEMBL15235842 | 0.75 | PLA2G2A (0.47) | FABP3SMN1; SMN2PLA2G2APLA2G1BPLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11841362-B2 | Method for the diagnosis of Niemann-Pick disease | CENTOGENE GMBH (DE) | 2023-12-12 | — | — | US | disclosed |
| US-20220187283-A1 | Method for the Diagnosis of Niemann-Pick Disease | CENTOGENE GMBH (DE) | 2022-06-16 | — | — | US | disclosed |
| US-11231412-B2 | Method for the diagnosis of Niemann-Pick disease | CENTOGENE GMBH (DE) | 2022-01-25 | — | — | US | disclosed |
| US-20200072819-A1 | Method for the Diagnosis of Niemann-Pick Disease | CENTOGENE GMBH (DE) | 2020-03-05 | — | — | US | disclosed |
| US-10422789-B2 | Method for the diagnosis of Niemann-Pick disease | CENTOGENE AG (DE) | 2019-09-24 | — | — | US | disclosed |
| US-10302664-B2 | Method for the diagnosis of Niemann-Pick disease | CENTOGENE AG (DE) | 2019-05-28 | — | — | US | disclosed |
| US-20180088107-A1 | Method for the Diagnosis of Niemann-Pick Disease | CENTOGENE GMBH (DE) | 2018-03-29 | — | — | US | disclosed |
| US-9910033-B2 | Method for the diagnosis of Niemann-Pick disease | CENTOGENE AG (DE) | 2018-03-06 | — | — | US | disclosed |