Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP5 | P51878 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.38 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.38 |
| ▸ | FLT3 | P36888 | 7/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 5/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928663 | 0.86 | HRH4 (0.51) | CASP1CASP4CASP5ADRB1NCF1 | |
| SCHEMBL19928666 | 0.80 | SRC (0.53) | FLT3AURKAKDRKITSRC | |
| SCHEMBL16809209 | 0.79 | NUDT1 (0.50) | CASP1CASP4CASP5ADRB1NCF1 | |
| SCHEMBL22457644 | 0.73 | CASP1 (0.47) | CASP1CASP4CASP5ADRB1NCF1 | |
| SCHEMBL14702329 | 0.73 | CASP1 (0.47) | CASP1CASP4CASP5ADRB1NCF1 | |
| SCHEMBL30376883 | 0.72 | CASP1 (0.53) | CASP1CASP4CASP5ADRB1NCF1 | |
| SCHEMBL14538233 | 0.72 | CASP1 (0.53) | CASP1CASP4CASP5ADRB1NCF1 | |
| SCHEMBL25493609 | 0.69 | HRH4 (0.54) | HRH4 | |
| SCHEMBL20905447 | 0.69 | KMT2A (0.51) | CASP1CASP4CASP5ADRB1NCF1 | |
| SCHEMBL18636739 | 0.69 | HRH4 (0.64) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908872-B2 | Methods to treat lymphoplasmacytic lymphoma | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-03-06 | — | — | US | disclosed |