Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 5/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGAV | P06756 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MC3R | P41968 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104081 | 0.86 | KDM4E (0.41) | NNMTITGB3ITGAVLMNATSHR | |
| SCHEMBL14610720 | 0.76 | ITGB3 (0.46) | NNMTITGB3ITGAVCXCR4ITGA2B | |
| SCHEMBL13995820 | 0.75 | ITGB3 (0.45) | ITGB3ITGAVCXCR4ITGA2B | |
| SCHEMBL17541073 | 0.72 | HTR2C (0.41) | — | |
| SCHEMBL30540616 | 0.71 | PIM1 (0.38) | NNMTPIM1MAP3K14LMNAADORA3 | |
| SCHEMBL16135650 | 0.70 | NNMT (0.53) | NNMTPIK3C3ASIC3 | |
| SCHEMBL23093250 | 0.69 | PARP10 (0.38) | NNMTASIC3 | |
| SCHEMBL279310 | 0.69 | UHRF1 (0.43) | NNMTASIC3 | |
| SCHEMBL21273854 | 0.69 | F7 (0.38) | NNMTPIM1ASIC3 | |
| SCHEMBL16496259 | 0.69 | PIM1 (0.42) | NNMTPIM1MAP3K14LMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-A1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | Suven Life Sciences Limited (IN) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018042362-A1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2018-03-08 | — | — | WO | disclosed |