Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.37 |
| ▸ | ITGAV | P06756 | 10/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.35 |
| ▸ | ITGB6 | P18564 | 4/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610720 | 0.90 | ITGB3 (0.46) | KDM4ENNMTITGB3ITGAVITGB5 | |
| SCHEMBL19928751 | 0.86 | NNMT (0.49) | TSHRKMT2ALMNANNMTITGB3 | |
| SCHEMBL5316288 | 0.76 | CRBN (0.41) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL13995820 | 0.75 | ITGB3 (0.45) | ITGB3ITGAVITGB5ITGB6ITGB8 | |
| SCHEMBL10209782 | 0.72 | HTR2C (0.44) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL14610993 | 0.71 | KDM4E (0.37) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL29827162 | 0.70 | TDP2 (0.44) | KDM4ETDP1ALOX15TSHRACMSD | |
| SCHEMBL23093250 | 0.69 | PARP10 (0.38) | NNMT | |
| SCHEMBL279310 | 0.69 | UHRF1 (0.43) | NNMTRAB9A | |
| SCHEMBL21273854 | 0.69 | F7 (0.38) | NNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447455-A | Nitrogen-containing heterocyclic compound | 首药控股(北京)股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| EP-4061373-A1 | METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | Angion Biomedica Corp. (US) | 2022-09-28 | — | — | EP | disclosed |