SCHEMBL19928970

SCHEMBL19928970

O=P(c1ccccc1)(c1ccccc1)c1ccc2ccc(-c3ccc4nc5c6ccccc6c6ccccc6n5c4c3)cc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.40
ALDH1A1 P00352 5/20 0.40
KDM4E B2RXH2 4/20 0.40
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 3/20 0.35
POLB P06746 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 2/20 0.33
TUBB4A P04350 1/20 0.32
TUBB P07437 1/20 0.32
TUBA3C P0DPH7 1/20 0.32
TUBA1B P68363 1/20 0.32
TUBA4A P68366 1/20 0.32
TUBB4B P68371 1/20 0.32
TUBB3 Q13509 1/20 0.32
TUBB2A Q13885 1/20 0.32
TUBB8 Q3ZCM7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19928966 0.97 HPGD (0.40) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL20276037 0.93 ALDH1A1 (0.45) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL19928981 0.93 ALDH1A1 (0.45) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL18118559 0.92 KDM4E (0.44) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL19960013 0.92 HPGD (0.38) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL18118561 0.91 KDM4E (0.41) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL19960008 0.91 HPGD (0.37) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL19959783 0.91 KDM4E (0.38) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL15479369 0.90 KDM4E (0.41) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2
SCHEMBL19928972 0.90 KDM4E (0.41) HPGDALDH1A1KDM4EKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11362280-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-06-14 US disclosed
US-11342508-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2022-05-24 US disclosed
US-10547008-B2 Organic light emitting device LG CHEM, LTD. (KR) 2020-01-28 US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 US disclosed
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2018-06-21 US disclosed
US-20180069180-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2018-03-08 US disclosed
US-20180069180-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11342508-B2 Organic light-emitting device CRY1, CRY2, NR2E3 HPGD 3262/4885ALDH1A1 103/4885KDM4E 2028/4885
US-20180175302-A1 ORGANIC LIGHT-EMITTING DEVICE CRY1, CRY2, NR2E3 HPGD 3262/4885ALDH1A1 103/4885KDM4E 2028/4885
US-11362280-B2 Organic light-emitting device CRY1, CRY2, NR2E3 HPGD 3262/4885ALDH1A1 103/4885KDM4E 2028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.