SCHEMBL19929280

SCHEMBL19929280

O=C(CCCNCCCCCNC(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA3 P07451 2/20 0.72
CA5A P35218 2/20 0.72
CA5B Q9Y2D0 2/20 0.72
CA14 Q9ULX7 2/20 0.72
CA12 O43570 1/20 0.72
CA2 P00918 1/20 0.72
CA4 P22748 1/20 0.72
CA6 P23280 1/20 0.72
CA7 P43166 1/20 0.72
CA9 Q16790 1/20 0.72
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
ALDH1A1 P00352 1/20 0.64
POLB P06746 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
HDAC6 Q9UBN7 1/20 0.62
EPHX1 P07099 1/20 0.58
FAAH O00519 9/20 0.44
CES1 P23141 5/20 0.44
CES2 O00748 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL570465 0.89 CA3 (0.91) CA3CA5ACA5BCA14CA12
SCHEMBL10228415 0.85 CA3 (1.00) CA3CA5ACA5BCA14CA12
SCHEMBL1274081 0.85 CA3 (1.00) CA3CA5ACA5BCA14CA12
SCHEMBL12936102 0.85 CA3 (1.00) CA3CA5ACA5BCA14CA12
SCHEMBL3142216 0.82 CA3 (0.95) CA3CA5ACA5BCA14CA12
SCHEMBL29982917 0.82 MEN1 (1.00) CA3CA5ACA5BCA14CA12
SCHEMBL27889238 0.80 ALDH1A1 (1.00) CA3CA5ACA5BCA14CA12
Trifluoroacetic Acid SCHEMBL1274516 0.79 CA3 (0.88) CA3CA5ACA5BCA14CA12
Trifluoroacetic Acid SCHEMBL1274119 0.79 CA3 (0.88) CA3CA5ACA5BCA14CA12
SCHEMBL27108364 0.79 MEN1 (0.68) CA3CA5ACA5BCA14CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174459-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (US) 2023-06-08 US disclosed
US-20180065918-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2018-03-08 US disclosed
US-9663449-B2 2017-05-30 US disclosed
US-20140121393-A1 LIPID CONTAINING FORMULATIONS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2014-05-01 US disclosed
US-8642076-B2 Lipid containing formulations TEKMIRA PHARMACEUTICALS CORPORATION 2014-02-04 US disclosed
US-20120046478-A1 LIPID CONTAINING FORMULATIONS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-02-23 US disclosed
US-8034376-B2 Lipid containing formulations Alnylam Pharamaceticals, Inc. (US) 2011-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065918-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 CA3 4765/4885CA5A 1940/4885CA5B 1996/4885
US-20230174459-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 CA3 4765/4885CA5A 1940/4885CA5B 1996/4885
US-20140121393-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 CA3 4765/4885CA5A 1940/4885CA5B 1996/4885
US-20120046478-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 CA3 4765/4885CA5A 1940/4885CA5B 1996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.