Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22499802 | 0.82 | PTGS1 (0.57) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 | |
| SCHEMBL19809307 | 0.82 | PTGS1 (0.57) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 | |
| SCHEMBL2951490 | 0.82 | PTGS1 (0.57) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 | |
| SCHEMBL21216981 | 0.79 | PTGS1 (0.59) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 | |
| SCHEMBL16556798 | 0.78 | PTGS1 (0.58) | PTGS1SLC6A2SLC6A4KCNH2SCN5A | |
| SCHEMBL5540739 | 0.76 | PTGS1 (0.48) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 | |
| SCHEMBL13281044 | 0.75 | PTGS1 (0.55) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 | |
| SCHEMBL13281394 | 0.75 | PTGS1 (0.55) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 | |
| SCHEMBL13281047 | 0.75 | PTGS1 (0.55) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 | |
| SCHEMBL13281155 | 0.75 | PTGS1 (0.55) | PTGS1SLC6A2SLC6A4KCNH2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065931-A1 | METHOD FOR PRODUCING 1-(4-HYDROXYPHENYL)-4-(4-TRIFLUOROMETHOXYPHENOXY)PIPERIDINE OR SALT THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065931-A1 | METHOD FOR PRODUCING 1-(4-HYDROXYPHENYL)-4-(4-TRIFLUOROMETHOXYPHENOXY)PIPERIDINE OR SALT THEREOF | DHPS, PAH, HPD | PTGS1 322/4885SLC6A2 1433/4885SLC6A4 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.