Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768325 | 0.95 | TLR8 (0.50) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL28519758 | 0.93 | KDM4E (0.51) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL28680926 | 0.93 | KDM4E (0.51) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL5749122 | 0.93 | KDM4E (0.51) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL11248732 | 0.93 | KDM4E (0.51) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL11228143 | 0.93 | KDM4E (0.51) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL28687866 | 0.93 | KDM4E (0.51) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL5750251 | 0.93 | KDM4E (0.51) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL5749879 | 0.93 | KDM4E (0.51) | TLR8GAAKDM4EALDH1A1GLA | |
| SCHEMBL30287368 | 0.92 | KDM4E (0.50) | TLR8GAAKDM4EALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130310623-A1 | AMINE GAS TREATMENT SOLUTIONS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-11-21 | — | — | US | disclosed |
| WO-2013173423-A1 | AMINE GAS TREATMENT SOLUTIONS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2013-11-21 | — | — | WO | disclosed |
| EP-2519532-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | Chevron Phillips Chemical Company LP (US) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011082192-A1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-07-07 | — | — | WO | disclosed |
| EP-0958338-B1 | LITHIUM COMPLEX GREASE WITH EXTENDED LUBRICATION LIFE | EXXONMOBIL RES & ENG CO (US) | 2011-03-09 | — | — | EP | disclosed |
| EP-1002027-B1 | GREASE CONTAINING DIAMINE CORROSION INHIBITORS | EXXONMOBIL RES & ENG CO (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0867500-B1 | Preparation of polyalphaolefin based greases | EXXONMOBIL RES & ENG CO (US) | 2001-10-24 | — | — | EP | disclosed |
| US-6239085-B1 | Grease composition containing pao, alkylaromatic synthetic fluid and white oil for industrial bearings | EXXON RESEARCH AND ENGINEERING COMPANY | 2001-05-29 | — | — | US | disclosed |
| EP-0958338-A4 | LITHIUM COMPLEX GREASE WITH EXTENDED LUBRICATION LIFE | EXXON RESEARCH ENGINEERING CO (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-1002027-A4 | GREASE CONTAINING DIAMINE CORROSION INHIBITORS | EXXON RESEARCH ENGINEERING CO (US) | 2000-05-24 | — | — | EP | disclosed |
| EP-1002027-A1 | GREASE CONTAINING DIAMINE CORROSION INHIBITORS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 2000-05-24 | — | — | EP | disclosed |
| EP-0958338-A1 | LITHIUM COMPLEX GREASE WITH EXTENDED LUBRICATION LIFE | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1999-11-24 | — | — | EP | disclosed |
| EP-0903398-A2 | Lubricating grease containing alkoxylated amine corrosion inhibitor | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1999-03-24 | — | — | EP | disclosed |
| WO-1998041599-A1 | GREASE CONTAINING DIAMINE CORROSION INHIBITORS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1998-09-24 | — | — | WO | disclosed |
| WO-1998011180-A1 | LITHIUM COMPLEX GREASE WITH EXTENDED LUBRICATION LIFE | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310623-A1 | AMINE GAS TREATMENT SOLUTIONS | GPX4, OAT, HNMT | TLR8 906/4885GAA 1110/4885KDM4E 2336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.