SCHEMBL19929588

SCHEMBL19929588

N[C@@H](CCCCNC(=S)CCc1ccc([124I])cc1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PLAAT3 P53816 1/20 0.40
PLAAT5 Q96KN8 1/20 0.40
PLAAT2 Q9NWW9 1/20 0.40
PLAAT4 Q9UL19 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
SIRT2 Q8IXJ6 2/20 0.38
SIRT1 Q96EB6 1/20 0.38
ALB P02768 2/20 0.37
OTC P00480 1/20 0.36
SLC5A1 P13866 1/20 0.36
GRIK1 P39086 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19929586 0.94 ALB (0.41) PLAAT3PLAAT5PLAAT2PLAAT4CA12
SCHEMBL22022014 0.88 PLAAT3 (0.45) PLAAT3PLAAT5PLAAT2PLAAT4CA12
SCHEMBL19929583 0.88 CA12 (0.39) PLAAT3PLAAT5PLAAT2PLAAT4CA12
SCHEMBL19933029 0.88 ALB (0.49) CA12CA1CA2CA9ALB
SCHEMBL19929581 0.88 CA12 (0.39) PLAAT3PLAAT5PLAAT2PLAAT4CA12
SCHEMBL19929582 0.88 FOLH1 (0.41) PLAAT3PLAAT5PLAAT2PLAAT4CA12
SCHEMBL19929576 0.88 HPGD (0.49) ALBOTCSLC5A1HPGD
SCHEMBL19929560 0.85 SIRT2 (0.40) PLAAT3PLAAT5PLAAT2PLAAT4SIRT2
SCHEMBL22021340 0.84 ALB (0.45) ALBOTCGRIK1
SCHEMBL19929578 0.84 ALB (0.53) ALBSLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2023-10-19 US disclosed
US-20180066298-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IL1RN, IL2RA, IL1A PLAAT3 1233/4885PLAAT5 3242/4885PLAAT2 2442/4885
US-20180066298-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IL1RN, IL2RA, IL1A PLAAT3 1233/4885PLAAT5 3242/4885PLAAT2 2442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.