Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 2/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22021344 | 0.94 | PLAAT3 (0.48) | PLAAT3PLAAT5PLAAT2PLAAT4CA12 | |
| SCHEMBL19929588 | 0.88 | PLAAT3 (0.40) | PLAAT3PLAAT5PLAAT2PLAAT4CA12 | |
| SCHEMBL19929582 | 0.88 | FOLH1 (0.41) | PLAAT3PLAAT5PLAAT2PLAAT4CA12 | |
| SCHEMBL19929581 | 0.88 | CA12 (0.39) | PLAAT3PLAAT5PLAAT2PLAAT4CA12 | |
| SCHEMBL19929583 | 0.88 | CA12 (0.39) | PLAAT3PLAAT5PLAAT2PLAAT4CA12 | |
| SCHEMBL19933029 | 0.88 | ALB (0.49) | CA12CA1CA2CA9ALB | |
| SCHEMBL22021352 | 0.84 | CA1 (0.44) | PLAAT3PLAAT5PLAAT2PLAAT4CA12 | |
| SCHEMBL24253361 | 0.84 | ALB (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4ALB | |
| SCHEMBL22021340 | 0.84 | ALB (0.45) | ALB | |
| SCHEMBL19011013 | 0.84 | ALB (0.56) | PLAAT3PLAAT5PLAAT2PLAAT4ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102348-A1 | THIOAMIDE-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF | DIMAGNO STEPHEN (US) | 2020-05-22 | — | — | WO | disclosed |