Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 10/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | CA9 | Q16790 | 9/20 | 0.43 |
| ▸ | CA12 | O43570 | 8/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19935012 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL13785420 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL734535 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL24238614 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL24824205 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL24806634 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL24806648 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL24294505 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL21730994 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL19525536 | 1.00 | CYP3A4 (0.59) | CYP3A4MAPTCYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125410-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | UNIV YALE (US) | 2026-05-07 | — | — | US | disclosed |
| US-20250388614-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | UNIV YALE (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4658263-A2 | COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS | Yale University (US) | 2025-12-10 | — | — | EP | disclosed |
| US-20250161460-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | UNIV YALE (US) | 2025-05-22 | — | — | US | disclosed |
| US-20250064944-A1 | MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-02-27 | — | — | US | disclosed |
| US-12234256-B2 | Molecular degraders of extracellular proteins | YALE UNIVERSITY (US) | 2025-02-25 | — | — | US | disclosed |
| WO-2025021833-A1 | MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-01-30 | — | — | WO | disclosed |
| WO-2025021829-A1 | MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-01-30 | — | — | WO | disclosed |
| US-12128105-B2 | Molecular degraders of extracellular proteins | YALE UNIVERSITY (US) | 2024-10-29 | — | — | US | disclosed |
| WO-2024163610-A2 | COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS | YALE UNIVERSITY (US) | 2024-08-08 | — | — | WO | disclosed |
| US-20230271994-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | UNIV YALE (US) | 2023-08-31 | — | — | US | disclosed |
| WO-2023028590-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY (US) | 2023-03-02 | — | — | WO | disclosed |
| WO-2023028597-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | YALE UNIVERSITY (US) | 2023-03-02 | — | — | WO | disclosed |
| US-20220033817-A1 | Targeting Ligands | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2022-02-03 | — | — | US | disclosed |
| US-11174481-B2 | Targeting ligands | Arrowhead Pharmaceuticals, Inc. (US) | 2021-11-16 | — | — | US | disclosed |
| US-20190256849-A1 | Targeting Ligands | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2019-08-22 | — | — | US | disclosed |
| US-10294474-B2 | Targeting ligands | Arrowhead Pharmaceuticals, Inc. (US) | 2019-05-21 | — | — | US | disclosed |
| WO-2018044350-A1 | TARGETING LIGANDS | ARROWHEAD PHARMACEUTICALS, INC (US) | 2018-03-08 | — | — | WO | disclosed |
| US-20180064819-A1 | Targeting Ligands | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2018-03-08 | — | — | US | disclosed |
| US-20180064819-A1 | Targeting Ligands | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271994-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, MSR1, LDLR | CYP3A4 4211/4885MAPT 4545/4885CYP2C9 4162/4885 |
| US-20220033817-A1 | Targeting Ligands | FABP1, SNRPE, HAVCR2 | CYP3A4 4688/4885MAPT 3947/4885CYP2C9 4796/4885 |
| US-20180064819-A1 | Targeting Ligands | FABP1, SNRPE, HAVCR2 | CYP3A4 4688/4885MAPT 3947/4885CYP2C9 4796/4885 |
| US-10294474-B2 | Targeting ligands | FABP1, SNRPE, HAVCR2 | CYP3A4 4688/4885MAPT 3947/4885CYP2C9 4796/4885 |
| US-20190256849-A1 | Targeting Ligands | FABP1, SNRPE, HAVCR2 | CYP3A4 4688/4885MAPT 3947/4885CYP2C9 4796/4885 |
| US-20260125410-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, COL2A1, FCGR2A | CYP3A4 4169/4885MAPT 4585/4885CYP2C9 3846/4885 |
| US-20250161460-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, MSR1, LDLR | CYP3A4 4211/4885MAPT 4545/4885CYP2C9 4162/4885 |
| US-20250064944-A1 | MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF | SNRPE, EXOSC5, DIS3 | CYP3A4 4801/4885MAPT 1736/4885CYP2C9 4681/4885 |
| US-12128105-B2 | Molecular degraders of extracellular proteins | ASGR1, MSR1, LDLR | CYP3A4 4211/4885MAPT 4545/4885CYP2C9 4162/4885 |
| US-11174481-B2 | Targeting ligands | FABP1, SNRPE, HAVCR2 | CYP3A4 4688/4885MAPT 3947/4885CYP2C9 4796/4885 |
| US-20250388614-A1 | MOLECULAR DEGRADERS OF EXTRACELLULAR PROTEINS | ASGR1, COL2A1, LDLR | CYP3A4 4311/4885MAPT 4539/4885CYP2C9 4004/4885 |
| US-12234256-B2 | Molecular degraders of extracellular proteins | ASGR1, MSR1, LDLR | CYP3A4 4211/4885MAPT 4545/4885CYP2C9 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.