Sugi Predict

Sugi Predict / Compounds / SCHEMBL1993041

SCHEMBL1993041

SCHEMBL1993041

C=C(C)C(=O)OC(COCc1ccccc1)COCc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.45
▸ SLC1A1 P43005 1/20 0.44
▸ CA1 P00915 4/20 0.44
▸ CA2 P00918 2/20 0.44
▸ CA7 P43166 2/20 0.44
▸ CA9 Q16790 2/20 0.44
▸ APOBEC3A P31941 1/20 0.44
▸ APOBEC3G Q9HC16 1/20 0.44
▸ TSHR P16473 1/20 0.41
▸ HTT P42858 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ FOLH1 Q04609 1/20 0.40
▸ PPARA Q07869 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789021 0.84 ALDH1A1 (0.55) ALDH1A1SLC1A1CA1CA2CA7
SCHEMBL25391226 0.81 APOBEC3A (0.37) ALDH1A1SLC1A1CA1CA2CA7
Iodide SCHEMBL25391622 0.80 APOBEC3A (0.36) ALDH1A1SLC1A1CA1CA2CA7
SCHEMBL25391233 0.80 RGS12 (0.39) SLC1A1CA1CA2CA7CA9
Iodide SCHEMBL25391625 0.80 RGS12 (0.41) CA1CA2CA7CA9APOBEC3A
SCHEMBL11657250 0.79 CA1 (0.53) ALDH1A1SLC1A1CA1CA2CA7
SCHEMBL10834752 0.79 ALDH1A1 (0.49) ALDH1A1SLC1A1CA1CA2CA7
SCHEMBL391732 0.79 APOBEC3A (0.49) ALDH1A1SLC1A1CA1CA2CA7
SCHEMBL24827422 0.79 ALDH1A1 (0.57) ALDH1A1SLC1A1CA1CA2CA7
SCHEMBL6385004 0.78 SMN1; SMN2 (0.44) ALDH1A1TSHRHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10251841-B2 Polymeric depots for localization of agent to biological sites TRUSTEES OF BOSTON UNIVERSITY (US) 2019-04-09 — — US disclosed
WO-2018041132-A1 MONOMER, POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF 广东东阳光药业有限公司 2018-03-08 — — WO disclosed
US-20140271489-A1 POLYMERIC DEPOTS FOR LOCALIZATION OF AGENT TO BIOLOGICAL SITES TRUSTEES OF BOSTON UNIVERSITY (US) 2014-09-18 — — US disclosed
US-20130195954-A1 FILMS AND PARTICLES THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2013-08-01 — — US disclosed
US-20130195954-A1 FILMS AND PARTICLES THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2013-08-01 — — US disclosed
US-20130195954-A1 FILMS AND PARTICLES THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2013-08-01 — — US disclosed
US-8338492-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2012-12-25 — — US disclosed
US-8338492-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2012-12-25 — — US disclosed
US-8338492-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2012-12-25 — — US disclosed
US-8334324-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2012-12-18 — — US disclosed
US-20120107365-A1 FILMS AND PARTICLES THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2012-05-03 — — US disclosed
US-20110152305-A1 FILMS AND PARTICLES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2011-06-23 — — US disclosed
US-20110152305-A1 FILMS AND PARTICLES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2011-06-23 — — US disclosed
US-20110152305-A1 FILMS AND PARTICLES THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2011-06-23 — — US disclosed
US-7671095-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2010-03-02 — — US disclosed
US-7671095-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2010-03-02 — — US disclosed
US-7671095-B2 Films and particles THE TRUSTEES OF THE BOSTON UNIVERSITY (US) 2010-03-02 — — US disclosed
US-20080075718-A1 Films and Particles THE TRUSTEES OF THE BOSTON UNIVERSITY 2008-03-27 — — US disclosed
US-20080075718-A1 Films and Particles THE TRUSTEES OF THE BOSTON UNIVERSITY 2008-03-27 — — US disclosed
US-20080075718-A1 Films and Particles THE TRUSTEES OF THE BOSTON UNIVERSITY 2008-03-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152305-A1 FILMS AND PARTICLES APOB, PGF, ACTB ALDH1A1 2505/4885SLC1A1 4813/4885CA1 3355/4885
US-10251841-B2 Polymeric depots for localization of agent to biological sites CD68, LPXN, CXCL12 ALDH1A1 3186/4885SLC1A1 4167/4885CA1 2868/4885
US-20130195954-A1 FILMS AND PARTICLES APOB, PGF, ACTB ALDH1A1 2505/4885SLC1A1 4813/4885CA1 3355/4885
US-20080075718-A1 Films and Particles APOB, PGF, ACTB ALDH1A1 2505/4885SLC1A1 4813/4885CA1 3355/4885
US-20140271489-A1 POLYMERIC DEPOTS FOR LOCALIZATION OF AGENT TO BIOLOGICAL SITES CD68, LPXN, CXCL12 ALDH1A1 3186/4885SLC1A1 4167/4885CA1 2868/4885
US-20120107365-A1 FILMS AND PARTICLES APOB, PGF, ACTB ALDH1A1 2505/4885SLC1A1 4813/4885CA1 3355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.