Pyrene

Pyrene

SCHEMBL1993071

c1cc2ccc3cccc4ccc(c1)c2c34.c1ccccc1

nearest known ligand 0.92

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.92
HSD17B10 Q99714 7/20 0.92
TSHR P16473 6/20 0.92
HPGD P15428 4/20 0.92
CYP3A4 P08684 3/20 0.92
CYP1A2 P05177 3/20 0.92
CYP1A1 P04798 2/20 0.92
CYP1B1 Q16678 2/20 0.92
THRB P10828 1/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
TDP1 Q9NUW8 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
MAPK1 P28482 2/20 0.50
ATM Q13315 1/20 0.50
ERBB2 P04626 1/20 0.48
FYN P06241 1/20 0.48
MAOA P21397 1/20 0.48
ACHE P22303 1/20 0.48
AHR P35869 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL4977930 1.00 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL223412 0.96 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL9130 0.96 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL1332849 0.96 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL29429699 0.96 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL1650929 0.96 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL27737703 0.93 ALDH1A1 (0.79) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL23319293 0.92 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL21693735 0.92 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL1275551 0.92 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106483111-A Application of the pyrene benzothiazole schiff bases on detection silver ion 华南师范大学 2017-03-08 CN claimed
CN-103234948-B Application of pyrene and derivative as photosensitive perssad deprotection sensibilization reagent in biological chip production UNIV CENTRAL SOUTH 2015-07-22 CN claimed
CN-1098526-C Incineration treatment method for radioactive combustible waste and special equipment thereof CHINESE RADIATION PROT RES INS (CN) 2003-01-08 CN claimed
CN-1232274-A Radioactive combustible waste incineration treatment process and special equipment thereof CHINESE RADIATION PROTECTION R (CN) 1999-10-20 CN claimed
US-11393660-B2 Gasification device and plasma shutter with a microwave plazma slowing system of the gasification device INING S.RO. (CZ) 2022-07-19 US disclosed
CN-109437159-B Preparation method of graphene-carbon nanotube double-component suspension 西北工业大学 2022-03-01 CN disclosed
CN-213506737-U Damper for diffusing coal gas at tail end of coke oven 山西东义煤电铝集团煤化工有限公司 2021-06-22 CN disclosed
CN-112806561-A Formula of chewing type cigarette substitute food 中卫清华园生物科技有限公司 2021-05-18 CN disclosed
EP-3686916-B1 GASIFICATION DEVICE AND PLASMA SHUTTER WITH SLOWING SYSTEM OF THE GASIFICATION DEVICE INING S R O (CZ) 2021-03-03 EP disclosed
CN-211753845-U Improved generation exhaust gas desulfurization denitrification facility 江苏华晖环保科技有限公司 2020-10-27 CN disclosed
EP-3686916-A1 GASIFICATION DEVICE AND PLASMA SHUTTER WITH SLOWING SYSTEM OF THE GASIFICATION DEVICE Ining s.r.o. (CZ) 2020-07-29 EP disclosed
CN-210727572-U Multifunctional environment-friendly snack vehicle 成都郎钾科技有限公司 2020-06-12 CN disclosed
CN-1844117-A Method for removing micro polynary arene in natural vitamine E ZHEJIANG WORLDBEST PHARMACEUTI (CN) 2006-10-11 CN disclosed
CN-1185440-C Method for treating organic halide by plasma incineration and industrial device ZHEJIANG JUSHENG FLUOROCHEMICA (CN) 2005-01-19 CN disclosed
CN-1098526-C Incineration treatment method for radioactive combustible waste and special equipment thereof CHINESE RADIATION PROT RES INS (CN) 2003-01-08 CN disclosed
CN-1232274-A Radioactive combustible waste incineration treatment process and special equipment thereof CHINESE RADIATION PROTECTION R (CN) 1999-10-20 CN disclosed
CN-1093219-A Water soluble solid aerosol for hygiene purpose TAN GUIZHONG (CN) 1994-10-12 CN disclosed
CN-2148471-Y Filtering cigarette holder LIU JUNSHAN (CN) 1993-12-08 CN disclosed
CN-2146865-Y Toxin-filtering health cigarette SU ZHONGJI (CN) 1993-11-24 CN disclosed
EP-0062237-A1 Process for the determination of the carcinogenicity of chemical or physical agents YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) 1982-10-13 EP disclosed