SCHEMBL19933764

SCHEMBL19933764

Cc1cc(-c2ccc(B3OC(C)(C)C(C)(C)O3)cc2)ncc1-c1cc(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 10/20 0.40
LPL P06858 9/20 0.40
DGAT1 O75907 2/20 0.39
HIF1A Q16665 1/20 0.33
SNCA P37840 1/20 0.33
TDO2 P48775 1/20 0.33
PDGFRB P09619 1/20 0.32
KDR P35968 1/20 0.32
FFAR1 O14842 1/20 0.31
LDHA P00338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19933732 0.89 DGAT1 (0.38) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL18015329 0.83 LIPG (0.57) LIPGLPLDGAT1SNCAPDGFRB
SCHEMBL19794344 0.82 LIPG (0.42) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL23018908 0.82 DGAT1 (0.35) DGAT1PDGFRBKDR
SCHEMBL18015347 0.82 LIPG (0.58) LIPGLPLDGAT1SNCATDO2
SCHEMBL19794342 0.80 LIPG (0.47) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL18015307 0.79 DGAT1 (0.44) LIPGLPLDGAT1HIF1ASNCA
SCHEMBL18015367 0.79 LIPG (0.56) LIPGLPLDGAT1SNCAPDGFRB
SCHEMBL19801337 0.79 LIPG (0.41) LIPGLPLDGAT1SNCAPDGFRB
SCHEMBL18015447 0.78 LIPG (0.47) LIPGLPLDGAT1TDO2PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3507294-B1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-02-24 EP disclosed
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices MERCK PATENT GMBH 2021-01-12 US disclosed
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-07-04 US disclosed
WO-2018041769-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES PARN, PUF60, PARG LIPG 4374/4885LPL 4558/4885DGAT1 2586/4885
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices PARN, PUF60, PARG LIPG 4374/4885LPL 4558/4885DGAT1 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.