SCHEMBL19794342

SCHEMBL19794342

Cc1cccc(-c2cnc(-c3ccc(B4OC(C)(C)C(C)(C)O4)cc3)cc2C)c1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 8/20 0.47
LPL P06858 7/20 0.47
DGAT1 O75907 1/20 0.42
ENPP3 O14638 2/20 0.37
LDHA P00338 1/20 0.36
ADORA1 P30542 1/20 0.36
PDGFRB P09619 3/20 0.36
KDR P35968 3/20 0.36
IRAK4 Q9NWZ3 1/20 0.35
PGR P06401 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18015367 0.89 LIPG (0.56) LIPGLPLDGAT1ENPP3LDHA
SCHEMBL18015329 0.89 LIPG (0.57) LIPGLPLDGAT1ENPP3LDHA
SCHEMBL18015447 0.88 LIPG (0.47) LIPGLPLDGAT1LDHAPDGFRB
SCHEMBL19794344 0.85 LIPG (0.42) LIPGLPLDGAT1ADORA1PDGFRB
SCHEMBL18015347 0.83 LIPG (0.58) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL21397945 0.81 LIPG (0.45) LIPGLPLDGAT1ENPP3LDHA
SCHEMBL19933764 0.80 LIPG (0.40) LIPGLPLDGAT1LDHAPDGFRB
SCHEMBL19933638 0.80 LIPG (0.46) LIPGLPLDGAT1ENPP3LDHA
SCHEMBL21390894 0.80 DGAT1 (0.53) LIPGLPLDGAT1PDGFRBKDR
SCHEMBL19801337 0.80 LIPG (0.41) LIPGLPLDGAT1LDHAPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices MERCK PATENT GMBH 2021-01-12 US disclosed
US-20200052213-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES MERCK PATENT GMBH (DE) 2020-02-13 US disclosed
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-07-04 US disclosed
US-20180026209-A1 Metal Complexes MERCK PATENT GMBH (DE) 2018-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202851-A1 BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES PARN, PUF60, PARG LIPG 4374/4885LPL 4558/4885DGAT1 2586/4885
US-10889604-B2 Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices PARN, PUF60, PARG LIPG 4374/4885LPL 4558/4885DGAT1 2586/4885
US-20180026209-A1 Metal Complexes AP3M1, AP2M1, SOD1 LIPG 3693/4885LPL 3416/4885DGAT1 1328/4885
US-20200052213-A1 BINUCLEAR METAL COMPLEXES AND ELECTRONIC DEVICES, IN PARTICULAR ORGANIC ELECTROLUMINESCENT DEVICES CONTAINING SAID METAL COMPLEXES BICRA, NCLN, IMMT LIPG 3633/4885LPL 3762/4885DGAT1 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.