Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HLCS | P50747 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22037753 | 0.80 | HLCS (0.55) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL11974146 | 0.79 | TDP1 (0.59) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL20342144 | 0.78 | TDP1 (0.45) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL10065849 | 0.77 | HLCS (0.39) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL21390226 | 0.74 | TDP1 (0.44) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL23476650 | 0.73 | HLCS (0.68) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL21553555 | 0.73 | HLCS (0.68) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL21515957 | 0.73 | HLCS (0.68) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL5891326 | 0.73 | HLCS (0.68) | HLCSTDP1MEN1ABL1LMNA | |
| SCHEMBL22769187 | 0.73 | HLCS (0.68) | HLCSTDP1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290528-A1 | METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING | Illumina, Inc. (US) | 2018-03-07 | — | — | EP | disclosed |