Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172883 | 0.83 | DYRK1A (0.60) | DYRK1AKDM4EPBRM1L3MBTL1MEN1 | |
| SCHEMBL29391821 | 0.83 | DYRK1A (0.60) | DYRK1AKDM4EPBRM1L3MBTL1MEN1 | |
| SCHEMBL23369695 | 0.80 | ALDH1A1 (0.53) | KDM4EMEN1KMT2APOLBTDP1 | |
| SCHEMBL14598930 | 0.76 | DYRK1A (0.60) | DYRK1AKDM4EPBRM1MEN1KMT2A | |
| SCHEMBL13940846 | 0.74 | DYRK1A (0.50) | DYRK1AKDM4EPBRM1POLBTDP1 | |
| SCHEMBL17755365 | 0.73 | KDM4E (0.53) | KDM4EPBRM1L3MBTL1MEN1KMT2A | |
| SCHEMBL14598933 | 0.69 | ABCG2 (0.64) | DYRK1AKDM4EMEN1KMT2APOLB | |
| SCHEMBL21889562 | 0.68 | PARP1 (0.44) | CDK5CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL13412893 | 0.65 | CSNK2A2 (0.46) | DYRK1APBRM1POLBTDP1TP53 | |
| SCHEMBL13560649 | 0.65 | KIF11 (0.56) | KDM4EPBRM1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646691-B2 | QUINACRIDONE PIGMENT COMPOSITIONS COMPRISING UNSYMMETRICALLY SUBSTITUTED COMPONENTS | BASF SE (DE) | 2018-03-07 | — | — | EP | disclosed |