Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | BMP1 | P13497 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 6/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 11/20 | 0.36 |
| ▸ | MMP3 | P08254 | 4/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21153293 | 1.00 | ACE (0.47) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL21153023 | 0.98 | ACE (0.46) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL19934873 | 0.91 | ACE (0.43) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL19934702 | 0.87 | ACE (0.43) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL21134710 | 0.84 | BMP1 (0.46) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL21153275 | 0.84 | BMP1 (0.46) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL19934743 | 0.84 | BMP1 (0.46) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL19934754 | 0.84 | BMP1 (0.46) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL21135087 | 0.84 | BMP1 (0.46) | ACEBMP1KDM4EMAPTTHRB | |
| SCHEMBL19934701 | 0.84 | BMP1 (0.46) | ACEBMP1KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508476-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018041245-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | 中国医学科学院放射医学研究所 | 2018-03-08 | — | — | WO | disclosed |