Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.38 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997808 | 0.94 | PADI4 (0.44) | ROCK2ROCK1CNR1LIPGPADI4 | |
| SCHEMBL1997265 | 0.88 | RECQL (0.46) | ROCK2ROCK1LIPGHRH1 | |
| SCHEMBL1996234 | 0.83 | CNR1 (0.46) | ROCK2CNR1PADI4MEN1MAPK1 | |
| SCHEMBL1993250 | 0.82 | ROCK2 (0.50) | ROCK2CNR1PADI4PIK3CDPIK3R2 | |
| SCHEMBL1991422 | 0.82 | RECQL (0.47) | LIPGHRH1 | |
| SCHEMBL1996125 | 0.82 | PADI4 (0.47) | ROCK2CNR1PADI4PIK3CDPIK3R2 | |
| SCHEMBL1995634 | 0.82 | PADI4 (0.47) | ROCK2CNR1PADI4HTR4 | |
| SCHEMBL1994502 | 0.80 | ROCK2 (0.44) | ROCK2CNR1PADI4HRH1ADRA1A | |
| SCHEMBL1992840 | 0.76 | KDM4E (0.46) | ROCK1CNR1PADI4PIK3CDPIK3R2 | |
| SCHEMBL1991767 | 0.75 | NPY1R (0.40) | ROCK2CNR1PADI4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | LTA4H 438/4885ROCK2 4260/4885ROCK1 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.