Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20812378 | 0.86 | FFAR1 (0.39) | FFAR1S1PR1S1PR5CHRM2FPR1 | |
| SCHEMBL18857284 | 0.86 | PAX8 (0.40) | FFAR1MAPTPAX8CYP3A4CYP2C9 | |
| SCHEMBL19401239 | 0.80 | PAX8 (0.48) | FFAR1PTAFRPAX8 | |
| SCHEMBL23240091 | 0.76 | NOTUM (0.35) | S1PR1LMNAMAPTHTTPAX8 | |
| SCHEMBL12892509 | 0.75 | ESR2 (0.41) | FFAR1 | |
| SCHEMBL21922392 | 0.74 | PAX8 (0.33) | FFAR1PTAFRLMNAMAPTSMN1; SMN2 | |
| SCHEMBL21165795 | 0.74 | KDM1A (0.36) | S1PR1LMNAMAPTHTTPAX8 | |
| SCHEMBL10476961 | 0.73 | APP (0.48) | FFAR1LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL19403092 | 0.73 | FFAR1 (0.33) | FFAR1S1PR1S1PR5PTAFRLMNA | |
| SCHEMBL18486758 | 0.73 | CYP3A4 (0.36) | LMNAMAPTHTTCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935513-B1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |