Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 6/20 | 0.48 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18857284 | 0.88 | PAX8 (0.40) | PAX8GRM5FFAR1DGAT1CYP11B2 | |
| SCHEMBL21526237 | 0.82 | FFAR1 (0.44) | PAX8FFAR1SLC18A3PDK2 | |
| SCHEMBL10476961 | 0.81 | APP (0.48) | GRM5FFAR1SLC18A3CYP11B2 | |
| SCHEMBL20811932 | 0.80 | PAX8 (0.34) | PAX8GRM5FFAR1 | |
| SCHEMBL19935705 | 0.80 | FFAR1 (0.40) | PAX8FFAR1PTAFR | |
| Cyclohexane SCHEMBL28575545 | 0.79 | NPC1 (0.50) | PAX8GRM5CHRNB2CHRNA4FFAR1 | |
| SCHEMBL18486758 | 0.78 | CYP3A4 (0.36) | — | |
| SCHEMBL8837766 | 0.77 | ABCB1 (0.43) | PAX8GRM5FFAR1 | |
| SCHEMBL21922392 | 0.76 | PAX8 (0.33) | PAX8FFAR1SLC18A3PTAFRCYP11B2 | |
| SCHEMBL3836703 | 0.76 | APP (0.50) | GRM5FFAR1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3739020-B1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-08-23 | — | — | EP | disclosed |
| EP-3739020-A1 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2020-11-18 | — | — | EP | disclosed |
| EP-3733816-A1 | ISOTHIOCYANATO-TOLANES | Merck Patent GmbH (DE) | 2020-11-04 | — | — | EP | disclosed |
| EP-3140369-B1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| WO-2017162716-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-09-28 | — | — | WO | disclosed |