Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23995488 | 0.79 | MDM2 (0.49) | HTR2AHTR2CHTR2BSLC6A3MDM2 | |
| SCHEMBL25004705 | 0.79 | MDM2 (0.49) | HTR2AHTR2CHTR2BSLC6A3MDM2 | |
| SCHEMBL1990780 | 0.78 | MAOB (0.48) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL1994726 | 0.77 | HTR2A (0.51) | HTR2AHTR2CHTR2BSLC6A3MDM2 | |
| SCHEMBL7509170 | 0.69 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL6586419 | 0.69 | HTR2A (0.50) | HTR2AHTR2CHTR2BSLC6A3MDM2 | |
| SCHEMBL6991920 | 0.69 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL6991918 | 0.69 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL2837243 | 0.69 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 | |
| SCHEMBL7509163 | 0.69 | KDM1A (0.60) | HTR2AHTR2CHTR2BSLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018377-A1 | Aminopropenoates as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-16 | — | — | US | disclosed |
| US-8476197-B2 | Aminopropenoates as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20110152322-A1 | Aminopropenoates as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152322-A1 | Aminopropenoates as Fungicides | AASDHPPT, DAO, AAAS | HTR2A 3519/4885HTR2C 3110/4885HTR2B 2360/4885 |
| US-20140018377-A1 | Aminopropenoates as Fungicides | ACMSD, AASDHPPT, AAAS | HTR2A 2276/4885HTR2C 1693/4885HTR2B 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.