Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.54 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.52 |
| ▸ | FABP1 | P07148 | 1/20 | 0.50 |
| ▸ | FABP6 | P51161 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448193 | 0.85 | CYP2D6 (0.59) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL5845328 | 0.81 | CYP2D6 (0.65) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL6800071 | 0.81 | CYP2D6 (0.65) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL14198659 | 0.81 | CYP2D6 (0.56) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL1831588 | 0.81 | CYP2D6 (0.56) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL25387117 | 0.80 | PCSK9 (0.58) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL9645509 | 0.80 | CYP2D6 (0.54) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL8237897 | 0.79 | PCSK9 (0.61) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL22241702 | 0.79 | PCSK9 (0.57) | CYP2D6FDPSPCSK9CXCR4FABP1 | |
| SCHEMBL10830140 | 0.79 | CYP2D6 (0.53) | CYP2D6FDPSPCSK9CXCR4FABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947237-B2 | Antimicrobial compounds and methods of making and using the same | BioVersys AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-20180065966-A1 | Antimicrobial Compounds And Methods Of Making And Using The Same | MELINTA THERAPEUTICS, INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065966-A1 | Antimicrobial Compounds And Methods Of Making And Using The Same | LPO, MPO, CAT | CYP2D6 1042/4885FDPS 515/4885PCSK9 1592/4885 |
| US-10947237-B2 | Antimicrobial compounds and methods of making and using the same | LPO, MPO, CAT | CYP2D6 1042/4885FDPS 515/4885PCSK9 1592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.