Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | PLEC | Q15149 | 1/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 10/20 | 0.55 |
| ▸ | KDM5A | P29375 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19936703 | 0.82 | HCAR3 (0.51) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL17938280 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL27894389 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL30780105 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL29114291 | 0.76 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL1731245 | 0.76 | GAA (1.00) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL22073753 | 0.75 | ALDH1A1 (0.38) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL19936552 | 0.74 | CYP3A4 (0.35) | ALDH1A1KDM4EGAAMAPTTHRB | |
| SCHEMBL23226747 | 0.74 | ERN1 (0.49) | KDM4EHCAR3 | |
| SCHEMBL13306362 | 0.74 | HCAR3 (0.55) | ALDH1A1KDM4EGAAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2594555-B1 | HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR | ASKA PHARM CO LTD (JP) | 2018-03-07 | — | — | EP | disclosed |