Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243031 | 0.82 | LCK (0.41) | POLBHCKBTKNPC1SMN1; SMN2 | |
| SCHEMBL13652939 | 0.79 | HSD17B10 (0.42) | NPC1ACACBSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL30526543 | 0.78 | PIK3CD (0.55) | NPC1ACACBSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL184566 | 0.78 | PIK3CD (0.55) | NPC1ACACBSMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL13218005 | 0.73 | LDHA (0.40) | POLBHCKBTKNPC1SMN1; SMN2 | |
| SCHEMBL23095399 | 0.71 | IRAK4 (0.44) | POLBNPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL19455004 | 0.71 | LDHA (0.39) | POLBHCKBTKNPC1SMN1; SMN2 | |
| SCHEMBL21665291 | 0.70 | ACHE (0.45) | — | |
| SCHEMBL13201318 | 0.69 | LDHA (0.37) | POLBHCKBTKNPC1ALDH1A1 | |
| SCHEMBL31290967 | 0.68 | BRAF (0.47) | HCKBTKNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402327-B1 | Acetamide compounds as glucokinase activators, their process and medicinal applications | IMPETIS BIOSCIENCES LTD (IN) | 2018-03-07 | — | — | EP | disclosed |