Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8737620 | 0.92 | TUBB4A (0.47) | TP53TDP1L3MBTL1PKMKMT2A | |
| SCHEMBL8736028 | 0.88 | TP53 (0.52) | TP53TDP1L3MBTL1PKMKMT2A | |
| SCHEMBL8734890 | 0.83 | PKM (0.46) | TP53TDP1L3MBTL1PKMKMT2A | |
| SCHEMBL15308262 | 0.81 | CFTR (0.39) | TP53MAPK1 | |
| SCHEMBL25492200 | 0.78 | TUBB4A (0.48) | TP53TDP1L3MBTL1PKMKMT2A | |
| SCHEMBL25492204 | 0.76 | GAA (0.49) | TP53PKMTSHRGAASMN1; SMN2 | |
| SCHEMBL25492192 | 0.76 | GAA (0.51) | TP53TDP1L3MBTL1KMT2ATSHR | |
| SCHEMBL19333109 | 0.75 | MEN1 (0.36) | TDP1L3MBTL1KMT2ATSHRGAA | |
| SCHEMBL8737136 | 0.74 | GAA (0.45) | TP53L3MBTL1KMT2AGAALMNA | |
| SCHEMBL21767266 | 0.74 | PKM (0.52) | TP53TDP1L3MBTL1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064718-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | ABIONYX PHARMA (FR) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064718-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USEFUL FOR CHOLESTEROL MOBILIZATION | CETP, LIPA, NPC1L1 | TP53 4671/4885TDP1 2336/4885L3MBTL1 2182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.