Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 2/20 | 0.30 |
| ▸ | CASP7 | P55210 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19942294 | 0.82 | ALDH1A1 (0.31) | ALDH1A1HPGDHSD17B10DYRK1A | |
| SCHEMBL24163736 | 0.79 | COMT (0.35) | ALDH1A1HPGDHSD17B10DYRK1A | |
| SCHEMBL24163733 | 0.76 | NPC1 (0.31) | ALDH1A1HPGDHSD17B10KDM4ETP53 | |
| SCHEMBL14341761 | 0.74 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10DYRK1AKDM4E | |
| SCHEMBL15069240 | 0.74 | ALDH1A1 (0.31) | ALDH1A1HPGDHSD17B10DYRK1AMAPT | |
| SCHEMBL21894547 | 0.70 | PIK3CG (0.33) | — | |
| SCHEMBL24163187 | 0.69 | — | — | |
| SCHEMBL21266713 | 0.67 | ALDH1A1 (0.32) | ALDH1A1HPGDHSD17B10DYRK1A | |
| SCHEMBL19942190 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10DYRK1A | |
| SCHEMBL25818110 | 0.65 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10DYRK1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065971-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065971-A1 | sGC STIMULATORS | GUCY1A2, PRKG1, GMPS | ALDH1A1 2650/4885HPGD 108/4885HSD17B10 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.