Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341761 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10DYRK1ASMPD3 | |
| SCHEMBL24163736 | 0.74 | COMT (0.35) | ALDH1A1HPGDHSD17B10COMTDYRK1A | |
| SCHEMBL27008214 | 0.67 | ALDH1A1 (0.39) | ALDH1A1HPGDHSD17B10COMTSMPD3 | |
| SCHEMBL21752735 | 0.67 | TDP1 (0.43) | ALDH1A1HSD17B10NPC1MAPTRAB9A | |
| SCHEMBL20528869 | 0.67 | ALDH1A1 (0.42) | ALDH1A1HPGDHSD17B10DYRK1ASMPD3 | |
| SCHEMBL24163730 | 0.67 | PIK3R1 (0.32) | — | |
| SCHEMBL20848275 | 0.66 | ALDH1A1 (0.38) | ALDH1A1HPGDHSD17B10SMPD3MAPT | |
| SCHEMBL19939404 | 0.65 | ALDH1A1 (0.37) | ALDH1A1HPGDHSD17B10DYRK1ANPC1 | |
| SCHEMBL3469124 | 0.65 | PDE10A (0.43) | ALDH1A1HPGDHSD17B10NPC1MAPT | |
| SCHEMBL3970342 | 0.65 | KDM4E (0.52) | ALDH1A1HPGDHSD17B10DYRK1ASMPD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133225-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023133229-A2 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-07-13 | — | — | WO | disclosed |