Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG2 | P78540 | 3/20 | 0.37 |
| ▸ | ARG1 | P05089 | 2/20 | 0.37 |
| ▸ | ODC1 | P11926 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | GGT1 | P19440 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18071344 | 1.00 | ARG2 (0.37) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL5704688 | 0.79 | MEN1 (0.38) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL21199502 | 0.79 | MEN1 (0.38) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL5704692 | 0.79 | MEN1 (0.38) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL4812451 | 0.77 | ODC1 (0.53) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL4812444 | 0.77 | ODC1 (0.53) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL4812447 | 0.77 | ODC1 (0.53) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL188441 | 0.76 | FDPS (0.41) | ODC1THRBMEN1ALDH1A1CYP1A2 | |
| SCHEMBL7203565 | 0.76 | ODC1 (0.47) | ARG2ARG1ODC1KDM4ELMNA | |
| SCHEMBL7203566 | 0.76 | ODC1 (0.47) | ARG2ARG1ODC1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066018-A1 | CONFORMATIONALLY STABLE ANALOGS OF THE RESPONSE SELECTIVE C5A AGONIST EP67 | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066018-A1 | CONFORMATIONALLY STABLE ANALOGS OF THE RESPONSE SELECTIVE C5A AGONIST EP67 | C5AR1, C5AR2, C3AR1 | ARG2 1101/4885ARG1 103/4885ODC1 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.