Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.69 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.69 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032814 | 0.83 | TXNRD1 (1.00) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL21096624 | 0.82 | TXNRD1 (0.63) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL2964985 | 0.81 | PDE7A (0.70) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL8973665 | 0.76 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL5024763 | 0.74 | TXNRD1 (0.58) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL8530183 | 0.74 | TXNRD1 (0.58) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL29419968 | 0.73 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL7597811 | 0.73 | TSHR (0.62) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL114132 | 0.73 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2MAPTLMNA | |
| SCHEMBL16678757 | 0.72 | TXNRD1 (0.53) | TXNRD1TXNRD3TXNRD2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295101-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-09-21 | — | — | US | disclosed |
| US-20180065941-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065941-A1 | PHENOTHIAZINE ANALOGUES AS MITOCHONDRIAL THERAPEUTIC AGENTS | GSR, COQ8A, TXNRD2 | TXNRD1 135/4885TXNRD3 247/4885TXNRD2 3/4885 |
| US-20230295101-A1 | THERAPEUTIC COMPOUNDS | CFTR, C1R, FURIN | TXNRD1 1515/4885TXNRD3 707/4885TXNRD2 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.