Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | PNMT | P11086 | 1/20 | 0.56 |
| ▸ | CD44 | P16070 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13590042 | 0.91 | PNMT (0.65) | ALOX15HSD17B10MAOBPNMTCD44 | |
| SCHEMBL29351494 | 0.91 | — | — | |
| SCHEMBL10612 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL4702076 | 0.88 | PNMT (0.62) | ALOX15HSD17B10MAOBPNMTCD44 | |
| Hydrochloric Acid SCHEMBL29371527 | 0.88 | PNMT (0.62) | ALOX15HSD17B10MAOBPNMTCD44 | |
| Methane SCHEMBL11147358 | 0.88 | PNMT (0.62) | ALOX15HSD17B10MAOBPNMTCD44 | |
| SCHEMBL28633341 | 0.88 | PNMT (0.62) | ALOX15HSD17B10MAOBPNMTCD44 | |
| Ammonia Solution, Strong SCHEMBL16296133 | 0.88 | PNMT (0.62) | ALOX15HSD17B10MAOBPNMTCD44 | |
| SCHEMBL29361921 | 0.88 | PNMT (0.62) | ALOX15HSD17B10MAOBPNMTCD44 | |
| Methane SCHEMBL27536218 | 0.88 | PNMT (0.62) | ALOX15HSD17B10MAOBPNMTCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3290424-A1 | SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVE AND PRODRUG THEREOF | Shionogi & Co., Ltd (JP) | 2018-03-07 | — | — | EP | disclosed |