Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13610341 | 0.83 | RAB9A (0.45) | MAPTLMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL13610373 | 0.82 | MEN1 (0.45) | MAPTLMNAKCNH2SCN5ASCN9A | |
| SCHEMBL13610296 | 0.77 | ALDH1A1 (0.51) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13610389 | 0.76 | ALDH1A1 (0.47) | MAPTRAB9AKDM4EALDH1A1 | |
| SCHEMBL13780226 | 0.74 | SMN1; SMN2 (0.47) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31028455 | 0.73 | FDPS (0.52) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL146973 | 0.73 | FDPS (0.52) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11445226 | 0.73 | SMN1; SMN2 (0.57) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13610473 | 0.72 | ABCB1 (0.44) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13610454 | 0.70 | ALDH1A1 (0.43) | MAPTLMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742635-B1 | SUBSTITUTED ORGANOSULFUR COMPOUNDS AND METHODS OF USING THEREOF | ACEA BIOSCIENCES INC (US) | 2018-03-07 | — | — | EP | disclosed |