SCHEMBL1994064

SCHEMBL1994064

CCCC(=O)Oc1ccc(F)c(F)c1F

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.49
BCL9 O00512 1/20 0.41
CTNNB1 P35222 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
RECQL P46063 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
LMNA P02545 1/20 0.36
EPHX2 P34913 1/20 0.36
TOP2A P11388 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1996406 0.90 KMT2A (0.51) ALOX15KDM4EMEN1RECQLKMT2A
SCHEMBL2939435 0.87 ALOX15 (0.47) ALOX15BCL9CTNNB1KDM4EMEN1
SCHEMBL1993192 0.86 ALOX15 (0.46) ALOX15KDM4ERECQLKMT2AALDH1A1
SCHEMBL28980518 0.85 ALOX15 (0.46) ALOX15BCL9CTNNB1KDM4EMEN1
SCHEMBL1997708 0.85 KMT2A (0.45) ALOX15BCL9CTNNB1KDM4EMEN1
SCHEMBL7043280 0.83 ALOX15 (0.47) ALOX15BCL9CTNNB1KDM4EMEN1
SCHEMBL10179983 0.83 ALOX15 (0.45) ALOX15BCL9CTNNB1KDM4EMEN1
SCHEMBL27709041 0.82 TSHR (0.47) ALOX15KDM4EMEN1RECQLKMT2A
SCHEMBL15763955 0.82 CES2 (0.42) ALDH1A1CES2CES1EPHX2
SCHEMBL1996675 0.81 BCL9 (0.41) ALOX15BCL9CTNNB1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109400459-A The preparation method of 2,4,5- trifluoro benzene acetic acid 浙江工业大学上虞研究院有限公司 2019-03-01 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
CN-109400459-A The preparation method of 2,4,5- trifluoro benzene acetic acid 浙江工业大学上虞研究院有限公司 2019-03-01 CN disclosed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-104112870-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2014-10-22 CN disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed
CN-102484281-A Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEM CORP 2012-05-30 CN disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
CN-100486580-C 6-aryl-7-halo-imidazo[1,2-A]pyrimidines as anticancer agents WYETH CORP (US) 2009-05-13 CN disclosed
CN-1856311-A 6-aryl-7-halo-imidazo [1, 2-A ] pyrimidines as anticancer agents WYETH CORP (US) 2006-11-01 CN disclosed
CN-1041202-C Novel Quinolone carboxylic acid derivative DONG WHA PHARM IND CO LTD (KR) 1998-12-16 CN disclosed
CN-1128995-A Novel Quinolone carboxylic acid derivative DONG WHA PHARM IND CO LTD (KR) 1996-08-14 CN disclosed