SCHEMBL10179983

SCHEMBL10179983

CCCC(=O)Oc1cc(F)c(F)c(F)c1F

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.45
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 2/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
BCL9 O00512 1/20 0.37
CTNNB1 P35222 1/20 0.37
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TOP2A P11388 1/20 0.33
TNF P01375 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27505452 0.90 KMT2A (0.48) ALOX15KDM4EKMT2ALMNAMEN1
SCHEMBL10181746 0.86 ALOX15 (0.42) ALOX15KDM4EKMT2AGLAGAA
SCHEMBL1996200 0.85 ALOX15 (0.44) ALOX15KDM4EALDH1A1KMT2AGLA
SCHEMBL28492966 0.84 ALOX15 (0.41) ALOX15KDM4EALDH1A1KMT2AGLA
SCHEMBL7541662 0.83 POLB (0.33) ALOX15KDM4EALDH1A1KMT2ALMNA
SCHEMBL1994064 0.83 ALOX15 (0.49) ALOX15KDM4EALDH1A1KMT2ABCL9
SCHEMBL10180593 0.82 ALOX15 (0.47) ALOX15KDM4EALDH1A1KMT2AGLA
SCHEMBL2000685 0.80 ALOX15 (0.41) ALOX15KDM4EALDH1A1KMT2AGLA
SCHEMBL21605344 0.79 CES2 (0.33) KDM4EL3MBTL1
SCHEMBL1996079 0.79 BCL9 (0.46) ALOX15KDM4EALDH1A1KMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130244122-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME ONUKI MASAMICHI (JP) 2013-09-19 US disclosed
US-20120219866-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS-ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-30 US disclosed
EP-2475041-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION, AND NON-AQUEOUS ELECTROLYTE BATTERY COMPRISING SAME Mitsubishi Chemical Corporation (JP) 2012-07-11 EP disclosed