Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | NOS2 | P35228 | 4/20 | 0.50 |
| ▸ | NOS3 | P29474 | 3/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632667 | 1.00 | NOS1 (0.50) | NOS1NOS2NOS3LOXL2F10 | |
| SCHEMBL27364938 | 0.94 | HRH3 (0.54) | NOS1NOS2NOS3LOXL2F10 | |
| SCHEMBL19941369 | 0.83 | NOS1 (0.53) | NOS1NOS2NOS3LOXL2KDM4E | |
| SCHEMBL14298196 | 0.81 | CA9 (0.52) | KDM4EHPGDHTTCA9SMN1; SMN2 | |
| SCHEMBL12360950 | 0.81 | CA9 (0.52) | KDM4EHPGDHTTCA9SMN1; SMN2 | |
| SCHEMBL7873597 | 0.80 | ALDH1A1 (0.50) | KDM4EHPGDHTTCA9SMN1; SMN2 | |
| SCHEMBL19938067 | 0.80 | ALDH1A1 (0.50) | KDM4EHPGDHTTCA9SMN1; SMN2 | |
| SCHEMBL19938064 | 0.77 | PLK1 (0.48) | KDM4EHPGDHTTCA9ALDH1A1 | |
| SCHEMBL27499995 | 0.77 | LOXL2 (0.56) | NOS1NOS2NOS3LOXL2F10 | |
| SCHEMBL10880173 | 0.76 | LOXL2 (0.50) | NOS1NOS2NOS3LOXL2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | CCNO, PTGDR, CCNE1 | NOS1 64/4885NOS2 52/4885NOS3 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.