Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19941005 | 0.88 | HTR1B (0.59) | HTR1BLOXL2KDM4ENCF1HTR1A | |
| SCHEMBL31175311 | 0.86 | LOXL2 (0.50) | HTR1BLOXL2FERMT2NCF1HTR1A | |
| SCHEMBL21816316 | 0.86 | LOXL2 (0.50) | HTR1BLOXL2FERMT2NCF1HTR1A | |
| SCHEMBL12410468 | 0.85 | LOXL2 (0.63) | LOXL2KDM4EFERMT2NCF1HTR1A | |
| SCHEMBL2333830 | 0.85 | NCF1 (0.51) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL23412273 | 0.84 | NCF1 (0.57) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL23412842 | 0.84 | NCF1 (0.57) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL23412835 | 0.84 | NCF1 (0.57) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL23413034 | 0.84 | NCF1 (0.57) | LOXL2NCF1HTR1AADRA1DADRA1A | |
| SCHEMBL23412358 | 0.84 | NCF1 (0.57) | LOXL2NCF1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | CCNO, PTGDR, CCNE1 | HTR1B 2753/4885LOXL2 4490/4885KDM4E 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.