Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NCF1 | P14598 | 7/20 | 0.47 |
| ▸ | CYBB | P04839 | 3/20 | 0.46 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23412378 | 0.89 | MAPT (0.52) | HTR1BKDM4ENCF1CYBBNOX5 | |
| SCHEMBL19941479 | 0.88 | HTR1B (0.56) | HTR1BKDM4ENCF1HTR1ALOXL2 | |
| SCHEMBL23412188 | 0.87 | NCF1 (0.51) | HTR1BKDM4ENCF1CYBBNOX5 | |
| SCHEMBL23412437 | 0.86 | NCF1 (0.58) | HTR1BKDM4ENCF1CYBBNOX5 | |
| SCHEMBL23412668 | 0.84 | NCF1 (0.59) | KDM4ENCF1CYBBNOX5MAPT | |
| SCHEMBL23412394 | 0.84 | NCF1 (0.59) | KDM4ENCF1CYBBNOX5MAPT | |
| SCHEMBL23412286 | 0.84 | NCF1 (0.59) | KDM4ENCF1CYBBNOX5MAPT | |
| SCHEMBL96151 | 0.83 | HTR1A (0.45) | HTR1BKDM4ENCF1CYBBNOX5 | |
| SCHEMBL5211140 | 0.83 | HTR1A (0.45) | HTR1BKDM4ENCF1CYBBNOX5 | |
| SCHEMBL9969535 | 0.83 | HTR1B (0.48) | HTR1BKDM4ENCF1CYBBNOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066007-A1 | Macrocyclic Compounds And Methods Of Making And Using The Same | CCNO, PTGDR, CCNE1 | HTR1B 2753/4885KDM4E 3457/4885NCF1 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.